Best boutique and luxury hotels in Panama City

We’ve discovered your new favourite luxury and boutique hotels in Panama City. Scroll on to find your first-class holiday in Panama…

  1. Panama City, Panama

    Amarla Boutique Hotel Casco Viejo

    Style

    Artsy-craftsy casa

    Setting

    Cobblestoned colonial quarter

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    An Amarla reed diffuser

    Price per night from (ex tax)$185.13

  2. Panama City , Panama

    American Trade Hotel

    Style

    Elan in Panama

    Setting

    Vibrant Casco Viejo

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    A welcome drink each on arrival

    Price per night from (ex tax)$234.00