Best boutique and luxury hotels in Panama

  1. Panama City, Panama

    Amarla Boutique Hotel Casco Viejo

    Style

    Artsy-craftsy casa

    Setting

    Cobblestoned colonial quarter

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    An Amarla reed diffuser

    Price per night from (ex tax)$206.82

  2. Panama City , Panama

    American Trade Hotel

    Style

    Elan in Panama

    Setting

    Vibrant Casco Viejo

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    A welcome drink each on arrival

    Price per night from (ex tax)$234.00

  3. Los Santos Province, Panama

    Sansara Surf & Yoga Resort

    Style

    Fine-flowing yoga escape

    Setting

    Surf-lapped Los Santos

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    A bottle of Champagne on arrival

    Price per night from (ex tax)$312.55

  4. Chiriquĩ Gulf, Panama

    Isla Palenque

    Style

    Palm-shaded casitas

    Setting

    Pacific-island wilderness

    Why book with us?

    Best-price guarantee

    Found your stay for less elsewhere? We'll match the price and give you a £50 voucher.

    Free Smith Extras on arrival

    From a bottle of champagne, to a spa treatment or a cookery class, you’ll get a little extra thank you with every booking

    Here for you 24/7

    Personal service from Smith24, our in-house travel specialists, 1 800 464 2040

    Anonymously reviewed

    Every hotel is reviewed by undercover tastemakers (and their partners)

    Smith Extra

    A bottle of wine and a bag of Boquete coffee worth US$90.

    Price per night from (ex tax)$670.32