Discover boutique hotels in South America

We've hand-picked the very best boutique and luxury hotels in South America to bring you our collection of stylish romantic retreats. Find your perfect hotel and get the low-down on holidays in South America – just choose your destination from the list below…

Destinations in South America

  • We’ve rounded up an ever-growing selection of boutique hotels, luxury hotel hideaways and romantic retreats in Argentina, from cosmopolitan capital Buenos Aires to the wilds of Patagonia…
  • From wild rainforest stays hidden in the Amazon to cocktail-fuelled luxury hotels near Copacabana Beach, Mr & Mrs Smith's round up of the best boutique hotels in Brazil is as diverse as the colourful South American country itself.
  • Discover Chile's diverse charms: make one of the best boutique hotels or luxury lodges in Chile your South American home from home, and you'll be perfectly poised to explore the deserts, mountains and coastline.
  • With soaring mountains, terracotta-coloured deserts and lush rainforests that hide the remnants of ancient civilisations, Colombia has some of the most enthralling landscapes in all of South America.
  • Go wild: the best boutique and luxury hotels in Ecuador are a dream for discerning adventurers. From the mainland out to the Galápagos, we've tracked down the most stylish places to stay.
  • Looking for a real adventure? Peru’s the perfect place, with rainforests, mountains and ancient cities waiting to be explored, from your base at one of our favourite boutique hotels.
  • Although it’s one of South America’s smallest countries, Uruguay entices plenty of travellers with its laid-back lifestyle… and we know some first-class places to stay.

Recommended offers

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  • Best-price guarantee

    Found your stay cheaper elsewhere? We’ll match the price and give you a $75 voucher.

  • Smith Extra on arrival

    Enjoy extras such as a picnic lunch, champagne or spa treatments, on the house