Mr & Mrs Smith

Art lovers are spoiled for choice here, with the Museum of the African Diaspora (+1 415 358 7200; www.moadsf.org) in the hotel, the Yerba Buena Center for the Arts (+1 415 978 2700; www.yerbabuenaarts.org) right opposite, and SFMoMA (+1 415 357 4000; www.sfmoma.org), San Francisco's Museum of Modern Art, just a few doors down on Third Street. SFMoMA has an awesome collection of paintings, sculpture, photography and design. Closed Wednesdays.

One of San Francisco's legendary cable-car stops is just a short stroll away – a ride on one of these is not to be missed. The California Street line runs from the Financial District up and over Nob Hill, via Chinatown; tickets cost US$3 each way, payable in cash.

There's always a buzzing atmosphere at Salt House (+1 415 543 8900) on Mission Street near the Yerba Buena gardens; its exposed bricks and European-style gastropub menu is perfect for Sunday brunch or upscale bar snacking. Townhall, 324 Howard Street (+1 415 980 3691), has funky chandeliers, a long bar, exposed pipework and sensational seasonal food. Ask the waiter for advice on the best dish of the day. The diverse wine list offers gems from the Napa and Sonoma valleys, as well as international favourites. Mecca SF (+1 415 621 7000) at 2029 Market Street has a boudoir feel, with a lively circular bar and glittering crystal chandeliers. Food is simple, seasonal, and delicious, and served up to a backdrop of soulful tunes.